Catharine of Bourbon (born: 1440 in Liège; died: 21 May 1469 in Nijmegen) was Duchess of Guelders from 1465-1469 by her marriage to Adolf, Duke of Guelders. She was a daughter of Charles I, Duke of Bourbon and his wife Agnes of Burgundy.
On 28 December 1463 in Bruges, she married Adolf II, Duke of Guelders, who succeeded his father Arnold as Duke of Guelders in 1465. Cahterine and Adolf had two children:
Philippa (1465-1547), who married in 1485 with Rene II, Duke of Lorraine (1451-1508)
Charles (1467-1538), who later became Duke of Guelders (1492–1538)
Catherine died in 1469 and was buried in the St. Stephen Church in Nijmegen.