Firms and tones while refining texture With Phospholipids and DMAE. This unique serum contains a proprietary blend of Neuropeptides that re-energize skin cells and help renew skin's appearance. It provides firming and toning benefits while helping to diminish the appearance of lines and wrinkles. It also enhances the benefits of other PerriconeMD treatment products. Ideal for skin showing accelerated signs of age. Neuropeptides - activates surface renewal of the dermis; combats sagging or crepey appearance of aging skin; improves the appearance of line sand wrinkles; delivers more toned supple and resilient skin. Patented. DMAE - provides ultimate firming benefits to young or sagging skin; improves muscle tone and enhances contour; addresses loss of elasticity; diminishes the appearance of lines and wrinkles. Patented. Made in USA.